
PROBIOBUCCO : Probiotic Strains for Oral Health

Domain Food
Technology Probiotic strains for biopreservation and nutrition
We looking for a partner for the formulation and commercialization of our probiotic strains
Contact us for detailed results by strain
Applications
The oral cavity is a complex bacterial ecosystem with a fragile equilibrium which can lead to the development of pathogenic species and oral diseases.
Facing the increasing resistance to antibiotics, replacement therapies that restore the microbial ecological balance are preferred.
- Oral probiotics, integrated into toothpaste, mouthwash, chewing-gums…, appear as an effective, safe and sustainable solution to prevent and treat oral diseases.
Description
The research team identified 6 probiotic strains among oral isolates of lactobacilli with benefits on oral health
- Strong co-aggregation with bacteria responsible for periodontal disease, halitosis, caries for a targeted action
- Good adherence on enamel and great integration to dental biofilm
- High antibacterial activity against pathogenic strains
- Control of the immune response and pro-inflammatory pathways induced by pathogens
- Safety with no transmission of antibiotic resistance genes to the oral ecosystem
- No production of substances leading to halitosis
- Persistence of beneficial effects due to survival test in salivary environment.
Benefits
Prevention and treatment of oral diseases: gingivitis and periodontitis, halitosis (bad breath), caries
- Development of commensal bacteria favorable to oral health and enhancing the immune response
- No proliferation of resistant bacterial species compared to antibiotics treatment
- Durable rebalancing of the oral microbiota
Inventors
Expertise in oral microbiology Library of more than 200 strains
Marie-Cécile BADET
Professor in Odontology at BORDEAUX University
Dentistry Practitioner
Contact
Christophe ZABAWINSKI
%63%2e%7a%61%62%61%77%69%6e%73%6b%69%40%61%73%74%2d%69%6e%6e%6f%76%61%74%69%6f%6e%73%2e%63%6f%6d
Jean-Luc CHAGNAUD
%6a%6c%2e%63%68%61%67%6e%61%75%64%40%61%73%74%2d%69%6e%6e%6f%76%61%74%69%6f%6e%73%2e%63%6f%6d