PROBIOBUCCO : Probiotic Strains for Oral Health

We looking for a partner for the formulation and commercialization of our probiotic strains
Contact us for detailed results by strain

Applications

The oral cavity is a complex bacterial ecosystem with a fragile equilibrium which can lead to the development of pathogenic species and oral diseases.

Facing the increasing resistance to antibiotics, replacement therapies that restore the microbial ecological balance are preferred.

• Oral probiotics, integrated into toothpaste, mouthwash, chewing-gums…, appear as an effective, safe and sustainable solution to prevent and treat oral diseases.

Description

The research team identified 6 probiotic strains among oral isolates of lactobacilli with benefits on oral health

• Strong co-aggregation with bacteria responsible for periodontal disease, halitosis, caries for a targeted action
• Good adherence on enamel and great integration to dental biofilm
• High antibacterial activity against pathogenic strains
• Control of the immune response and pro-inflammatory pathways induced by pathogens
• Safety with no transmission of antibiotic resistance genes to the oral ecosystem
• No production of substances leading to halitosis
• Persistence of beneficial effects due to survival test in salivary environment.

Benefits

Prevention and treatment of oral diseases: gingivitis and periodontitis, halitosis (bad breath), caries

• Development of commensal bacteria favorable to oral health and enhancing the immune response
• No proliferation of resistant bacterial species compared to antibiotics treatment
• Durable rebalancing of the oral microbiota