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Human Diffuse Midline Glioma histone mutant cell line

Domaine Santé et Bien-être

Technologie Ingénierie tissulaire et cellulaire

Applications

  • 3D cell culture
  • Assay development
  • Drug development
  • Drug resistance
  • High-throughput screening

Innovative Solution

Human DMG histone mutant cell line established from a biopsy at CHU Bordeaux

Product category: Human cells
Organism: homo sapiens, human
Product format: frozen
Main feature: Product type : cell model
Disease: Diffuse Midline Glioma

Publication: Farah Rahal, Caroline Capdevielle, Benoit Rousseau, Julien Yzotte, Jean-William Dupuy, David Cappellen, Guillaume Chotard, Mélissa Ménard, Justine Charpentier, Vincent Jecko, Charline Caumont, Edouard Gimbert, Christophe F Grosset, Martin Hagedorn, An EZH2 blocker sensitizes histone mutated diffuse midline glioma to cholesterol metabolism inhibitors through an off-target effect, Neuro-Oncology Advances, 2022, vdac018,
https://doi.org/10.1093/noajnl/vdac018

Advantages 

  • Very fast-growing glioma cells
  • Homogenous cell morphology
  • Same mutation as original biops

Inventeurs

Developed by Martin Hagedorn MD, PhD U1312 - BRIC (Inserm, université de Bordeaux)

Propriété intellectuelle

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PARTERSHIPS

Licensing 

 

Contact

Laura BERGEON
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+33 (0)7 64 74 46 94

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